Channel: MedCram - Medical Lectures Explained CLEARLY

Category: Education

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Description: Dr. Roger Seheult of MedCram explains new research on Neu5Gc, a sialic acid molecule found in meat and dairy, and how it may contribute to severe COVID-19 symptoms, inflammation, and certain chronic diseases and cancers. Roger Seheult, MD is the co-founder and lead professor at MedCram medcram.com He is Board Certified in Internal Medicine, Pulmonary Disease, Critical Care, and Sleep Medicine and an Associate Professor at the University of California, Riverside School of Medicine. Interviewer: Kyle Allred, Physician Assistant, Producer, and Co-Founder of MedCram.com This video was recorded on May 13, 2021 TOPICS IN THIS VIDEO INCLUDE: 00:00 Introduction to sialic acids and why they’re important 00:39 What are sialic acids? 01:53 Introduction to Neu5Ac (in humans) & Neu5Gc (in other mammals) 03:41 Why are Neu5Ac and Neu5Gc important? 05:41 Human antibodies against Neu5Gc-glycans, chronic inflammation, & xenosialitis 07:21 French NutriNet-Sante study and “Gcemic Index” of foods 08:40 Does just red meat contain Neu5Gc? What about poultry, eggs, & fish? 09:14 Neu5Gc intake differences in men & women 10:26 Association between BMI, plant-based diets, & sialic acids 13:02 Cycle of obesity & inflammation 13:30 Biologic therapy & coronary inflammation 14:51 Dr. Esselstyn’s work on diet & coronary artery disease 16:01 Risks of meat consumption - processed versus unprocessed 20:00 Health benefits of red meat consumption 22:01 Summary of diets & associated outcomes, looking ahead to COVIDENCE UK Study LINKS / REFERENCES: Mechanism of uptake and incorporation of the non-human sialic acid N-glycolylneuraminic acid into human cells (Journal of Biological Chemistry) | pubmed.ncbi.nlm.nih.gov/15557321 From “Serum Sickness” to “Xenosialitis”: Past, Present, and Future Significance of the Non-human Sialic Acid Neu5Gc (Frontiers in Immunology) | frontiersin.org/articles/10.3389/fimmu.2019.00807/full Association between Neu5Gc carbohydrate and serum antibodies against it provides the molecular link to cancer: French NutriNet-Santé study (BMC) | ncbi.nlm.nih.gov/pmc/articles/PMC7510162 Adventist Health Study-2 (Loma Linda University Health) | adventisthealthstudy.org/studies/AHS-2 Association of Biologic Therapy With Coronary Inflammation in Patients With Psoriasis as Assessed by Perivascular Fat Attenuation Index (JAMA) | pubmed.ncbi.nlm.nih.gov/31365032 A plant-based diet and coronary artery disease: a mandate for effective therapy (Journal of Geriatric Cardiology) | ncbi.nlm.nih.gov/pmc/articles/PMC5466936 Meat consumption and risk of 25 common conditions: outcome-wide analyses in 475,000 men and women in the UK Biobank study (BMC) | bmcmedicine.biomedcentral.com/articles/10.1186/s12916-021-01922-9#citeas The COVIDENCE UK Research Study has been developed in response to the outbreak of coronavirus disease (Queen Mary University of London) | qmul.ac.uk/covidence/about-the-covidence-uk-study All coronavirus updates are at MedCram.com (including more discussion on: does red meat cause cancer, cardiovascular disease, sialic acid, dairy and red meat cancer, COVID 19 Vaccines, and more). SUBSCRIBE TO THE MEDCRAM YOUTUBE CHANNEL: youtube.com/user/MEDCRAMvideos?sub_confirmation=1 Get notified of new videos by hitting the bell icon: MEDCRAM WORKS WITH MEDICAL PROGRAMS AND HOSPITALS: MedCram offers group discounts for students and medical programs, hospitals, and other institutions. Contact us at customers@medcram.com if you are interested. MEDIA CONTACT: Media Contact: customers@medcram.com Media contact info: medcram.com/pages/media-contact Video Produced by Kyle Allred FOLLOW US ON SOCIAL MEDIA: facebook.com/MedCram twitter.com/MedCramVideos instagram.com/medcram DISCLAIMER: MedCram medical videos are for medical education and exam preparation, and NOT intended to replace recommendations from your doctor. #COVID19 #SialicAcid #Neu5Gc