Channel: Speed Pharmacology

Category: Education

Tags: thrombinantithrombotic drugsthrombusvitamin kclotting cascadeheparinthrombolyticsanticoagulantsaspirinenoxaparinheparin mechanism of actionanticoagulants nursingwarfarin mechanism of actionanticoagulant drugsblood thinnersbloodanticoagulants pharmacologywarfarinanticoagulant drugs pharmacologycoagulation cascadeantiplatelet drugsblood pharmacologyantiplateletsantiplatelet drugs pharmacologyfactor xablood clotantithrombotics

Description: 👉📝Want study notes for this presentation? Join Patreon at patreon.com/speedpharmacology Anticoagulants, commonly referred to as blood thinners, are drugs that prevent or reduce coagulation of blood, prolonging the clotting time. Antiplatelet drugs, also known as a platelet aggregation inhibitors, decrease platelet aggregation and inhibit clot formation. These drugs play an important role in the treatment of various disorders such as myocardial infarction, thrombotic stroke and venous thromboembolism. This pharmacology lecture covers topics such as pathophysiology of blood clot formation and platelet function; activation, aggregation, cross-linking; ADP receptors, glycoprotein IIb/IIIa receptors, cyclooxygenase-1 (COX-1) enzyme, fibrinogen, fibrin mesh, coagulation cascade; intrinsic & extrinsic pathways, clotting factors, antithrombin, heparin induced thrombocytopenia, INR, plasmin, and plasminogen; mechanism of action of platelet inhibitors, anticoagulants, thrombolytic agents, and drugs used for treatment of bleeding. Drugs mentioned include; Aspirin, Clopidogrel, Ticagrelor, Ticlopidine, Prasugrel, Abciximab, Eptifibatide, Tirofiban, Heparin, low molecular weight heparins; Enoxaparin, Dalteparin, Protamine sulfate, Apixaban, Rivaroxaban, Univalent & Bivalent direct thrombin inhibitors; Argatroban, Dabigatran, Bivalirudin, Desirudin, Warfarin, Vitamin K, Alteplase, Reteplase, Tenecteplase, Urokinase, Streptokinase, Aminocaproic acid, Tranexamic acid. Thanks for watching and don't forget to SUBSCRIBE, hit the LIKE button👍 and click the BELL button🔔 for future notifications!!! 0:00 Platelet plug formation 2:04 Platelet aggregation inhibitors 5:34 Coagulation cascade 7:38 Anticoagulants 12:03 Warfarin 14:11 Thrombolytics